Professor Nicole Appleberry's research and teaching interests focus on the legal issues involved when vulnerable populations are caught up in systems beyond their experience and meaningful control—thus the intersection of tax law with other specialties such as poverty, disability, and domestic violence law, the empowerment of adversaries through mediation, and advancing social justice and developing legal skills through dialogue.

Professor Appleberry was an assistant prosecuting attorney in Livingston County, Michigan, from 1995 to 1999, focusing on juvenile delinquency, domestic violence, and child abuse and neglect. She is currently of counsel at Ferguson, Widmayer & Clark, PC in Ann Arbor, where she specializes in tax-related matters. She is a civil mediator, was chair of the Practice and Procedure Committee of the Taxation Section of the State Bar of Michigan, and served as co-chair of the Taxation Section of the Washtenaw County Bar Association. In 2017, she was nominated for a Golden Apple Award, the only University-wide student-nominated award that recognizes outstanding teaching.